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  • Psoromic Acid
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Psoromic Acid

An inhibitor of Rab geranylgeranyl transferase and P. falciparum FAS II enzymes

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Psoromic Acid的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 500ug
    ￥2200.00
    1760.00
    - +
  • 2.5mg
    ￥8637.00
    6910.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci21336
  • CAS: 7299-11-8
  • 别名: 茶痂衣酸
  • 分子式: C18H14O8
  • 分子量: 358.3
  • 纯度: >98%
  • 溶解度: DMSO: Soluble,Ethanol: Soluble
  • 储存: Store at -20°C
  • 库存: 现货

Background

Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 uM) and P. falciparum fatty acid synthesis (FAS) II. It shows cytotoxic effects on primary rat cerebral cortex and human cancer U87MG cell lines in vitro (IC50s = 79.40 and 56.22 mg/L, respectively). It also is cytotoxic against human KB cancer cells (IC50 = 31.6 uM). It shows moderate activity against liver stage P. beghei (IC50 = 31.6 uM) and drug-resistant blood stage P. falciparum (IC50 = 29.2 uM). The maximum tolerated dose in zebrafish larvae is 15.5 uM.

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