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  • bpV(pic) (potassium hydrate)
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bpV(pic) (potassium hydrate)

A PTEN inhibitor

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bpV(pic) (potassium hydrate)的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 5mg
    ￥1437.00
    1150.00
    - +
  • 25mg
    ￥6300.00
    5040.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci21678
  • CAS: 148556-27-8
  • 别名: Bisperoxovanadium(pic)
  • 分子式: C6H4NO7V.2K [2H2O]
  • 分子量: 367.3
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C, protect from light
  • 库存: 现货

Background

bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM). It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM). bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.

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