安捷凯生物医药
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  • Reticulol
Reticulol的可视化放大

Reticulol

A cAMP phosphodiesterase and DNA topoisomerase I inhibitor

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

Reticulol的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥2037.00
    1630.00
    - +
  • 1mg
    ￥3662.00
    2930.00
    - +
  • 5mg
    ￥16112.00
    12890.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci21744
  • CAS: 26246-41-3
  • 别名: 网状菌醇
  • 分子式: C11H10O5
  • 分子量: 222.2
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Reticulol is an isocoumarin derivative produced by certain species of Streptomyces that inhibits cAMP phosphodiesterase (IC50 = 41 uM). It also inhibits DNA topoisomerase I when used at a concentration of 45 uM in B16F10 melanoma cells. Reticulol has antifungal activity against T. mentagrophyes with a MIC of 1.8 uM. It is cytotoxic against A427 human lung and B16F10 mouse melanoma cells at concentrations of 25 and 200 uM, respectively, and inhibits lung metastasis in mice.

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