Emamectin B1a

An insecticide

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库存: 现货

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1mg

￥5687.00

4550.00

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5mg

￥19662.00

15730.00

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货号: ajci22022
CAS: 121124-29-6
别名: 依马菌素B1A
分子式: C49H75NO13
分子量: 886.1
纯度: >98%
溶解度: DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble
储存: Store at -20°C, protect from light
库存: 现货

Background

Emamectin B1a is a semi-synthetic derivative of avermectin B1a . It binds to GABAA receptors (Ki = 17.6 nM in rat brain membranes), including those containing β1, β2, or β3 subunits (IC50s = 57, 210, and 49.8 nM for α1β1γ2, α1β2γ2, and α1β3γ2 subunits, respectively), and potentiates the GABA response. Emamectin B1a also binds to and inhibits glycine receptors (IC50 = 218 nM in rat spinal cord). Emamectin B1a induces mortality in 90% of S. exigua larvae in a diet incorporation assay at a dose of 1.067 ng/ml, which is approximately 1,500-fold more toxic than avermectin B1. It is effective against neonate S. eridania larvae in a foliage spray bioassay and when applied topically.