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  • Trapoxin A
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Trapoxin A

Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor.

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Trapoxin A的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 1mg
    ￥3225.00
    2580.00
    - +
  • 5mg
    ￥11175.00
    8940.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci22072
  • CAS: 133155-89-2
  • 别名:
  • 分子式: C34H42N4O6
  • 分子量: 602.7
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor. It inhibits HDAC activity in a concentration-dependent and irreversible manner. Trapoxin A inhibits proliferation of NIH3T3 cells transformed by the oncogene v-sis (sis/NIH3T3; IC50 = ~200 ng/ml) and has detransformation activity, flattening sis/NIH3T3 cells when used at a concentration of 1 ng/ml. It also halts the cell cycle at the G2 phase in 3Y1 fibroblasts when used at a concentration of 10 nM and inhibits growth of TR303 cells resistant to trichostatin A at a concentration of 50 ng/ml.

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