Background
JQ-1 carboxylic acid is a highly potent, selective and cell-permeable BRD4 inhibitor with IC50s of 77 nM and 33 nM for BRD4(1) and BRD4(2), respectively.
参考文献:
[1]. James Elliott Bradner, et al. Male contraceptive compositions and methods of use. Patent WO 2011143657 A1.
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