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  • Lazertinib
Lazertinib的可视化放大

Lazertinib

An irreversible inhibitor of mutant EGFRs

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Lazertinib的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 5mg
    ¥1212.00
    970.00
    - +
  • 10mg
    ¥2012.00
    1610.00
    - +
  • 50mg
    ¥4525.00
    3620.00
    - +
  • 100mg
    ¥8525.00
    6820.00
    - +
已选 0 0
金额: ¥0.00
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  • 货号: ajci22678
  • CAS: 1903008-80-9
  • 别名: YH25448; GNS-1480
  • 分子式: C30H34N8O3
  • 分子量: 554.64
  • 纯度: >98%
  • 溶解度: DMSO : 9 mg/mL (16.23 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Lazertinib is a potent, highly mutant-selective, blood-brain barrier permeable, orally available and irreversible third-generation EGFR tyrosine kinase inhibitor, and can be used in the research of non-small cell lung cancer.


Lazertinib (YH25448) is a potent, highly mutant-selective, blood-brain barrier permeable, orally available and irreversible third-generation EGFR tyrosine kinase inhibitor, and can be used in the research of non-small cell lung cancer. Lazertinib targets both T790M mutation and activating EGFR mutations (EGFRm) while sparing wild type[1].

参考文献:
[1]. Byoung Chul Cho, et al. YH25448, a 3rd Generation EGFR-TKI, in Patients with EGFR-TKI-resistant NSCLC: Phase I/II Study Results.

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