7α-hydroxy-4-Cholesten-3-one

A metabolite of 7α-hydroxy cholesterol

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1mg

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货号: ajci64416
CAS: 3862-25-7
别名: 7-羟基-4-胆甾烯-3-酮
分子式: C27H44O2
分子量: 400.6
纯度: >98%
溶解度: Slightly soluble in methanol and chloroform
储存: Store at -20°C
库存: 现货

Background

7α-hydroxy-4-Cholesten-3-one is a metabolite of 7α-hydroxy cholesterol and an intermediate in the biosynthesis of bile acids.[1]? Plasma levels of 7α-hydroxy-4-cholesten-3-one positively correlate with the rate of bile acid synthesis in humans and are increased in patients following ileal resection.[2]

Reference:
[1]. Russell, D.W. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 72, 137-174 (2003).
[2]. Axelson, M., Aly, A., and Sj?vall, J. Levels of 7α-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in man. FEBS Lett. 239(2), 324-328 (1988).