Pentaacetylquercetin

A quercetin derivative with diverse biological activities

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库存: 现货

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10mg

￥787.00

630.00

- +
50mg

￥2562.00

2050.00

- +
100mg

￥4287.00

3430.00

- +
500mg

￥19312.00

15450.00

- +

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货号: ajci64620
CAS: 1064-06-8
别名: Pentaacetylquercetin
分子式: C25H20O12
分子量: 512.4
纯度: >98%
溶解度: DMF: 30 mg/mL,DMSO: 30 mg/mL,DMSO:PBS(pH 7.2) (1:4): 1 mg/mL,Ethanol: 2 mg/mL
储存: Store at -20°C
库存: 现货

Background

Pentaacetylquercetin is a pentaacetylated derivative of the flavonoid quercetin that has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in vitro (IC50 = 3.74 μg/ml) and inhibits iron(II) chloride-induced lipid peroxidation in rat liver mitochondria (IC50 = 20.2 μg/ml). Pentaacetylquercetin inhibits LPS-induced increases in nitrite (IC50 = 8.7 μM) and PGE2 production, as well as inducible nitric oxide synthase (iNOS) and COX-2 levels, in RAW 264.7 cells when used at concentrations of 20 and 40 μM. It also inhibits the growth of HL-60, U937, and SK-MEL-1 cells (IC50s = 38, 25, and 58 μM, respectively).