(±)-γ-Tocopherol

A form of vitamin E

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库存: 现货

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5mg

￥625.00

500.00

- +
10mg

￥1063.00

850.00

- +
25mg

￥2000.00

1600.00

- +
50mg

￥3875.00

3100.00

- +

已选 0 种 0 瓶

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货号: ajci64762
CAS: 7616-22-0
别名: 3,4-二氢-2,7,8-三甲基-2-(4,8,12-三甲基十三烷)-2H-1-苯并吡喃-6-醇
分子式: C28H48O2
分子量: 416.7
纯度: >98%
溶解度: DMF: miscible,DMSO: miscible,Ethanol: miscible,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
储存: 4°C, protect from light
库存: 现货

Background

(±)-γ-Tocopherol is a form of vitamin E with antioxidant and anti-inflammatory properties. It traps and detoxifies reactive nitrogen oxide species, including nitrogen dioxide, in cell-free assays. It also reduces the synthesis of prostaglandin E2 induced by LPS in RAW 264.7 macrophages and by IL-1β in A549 cells (IC50s = 7.5 and 4 μM, respectively). (±)-γ-Tocopherol (10 μM) inhibits LPS-induced nitrite release and inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells and reduces COX-2 activity in A549 cells pretreated with IL-1β. Serum levels of (±)-γ-tocopherol are decreased in patients with cardiovascular disease.