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  • 1-Arachidonoyl Glycerol
1-Arachidonoyl Glycerol的可视化放大

1-Arachidonoyl Glycerol

An endogenous CB receptor ligand

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1-Arachidonoyl Glycerol的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 1mg
    ¥325.00
    260.00
    - +
  • 5mg
    ¥1487.00
    1190.00
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  • 10mg
    ¥2650.00
    2120.00
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  • 25mg
    ¥5737.00
    4590.00
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  • 货号: ajci65180
  • CAS: 35474-99-8
  • 别名: 甘油花生四烯酸酯
  • 分子式: C23H38O4
  • 分子量: 378.6
  • 纯度: >98%
  • 溶解度: Ethanol: Miscible,Ethanol:PBS (1:2): 3 mg/ml
  • 储存: Store at -80°C, protect from light
  • 库存: 现货

Background

The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.

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