9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2

A potent PGE2 analog

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库存: 现货

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数量
500ug

￥762.00

610.00

- +
1mg

￥1437.00

1150.00

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5mg

￥6075.00

4860.00

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10mg

￥10637.00

8510.00

- +

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货号: ajci65182
CAS: 61263-35-2
别名: 甲烯前列素
分子式: C23H38O4
分子量: 378.6
纯度: >98%
溶解度: DMF: >100 mg/ml (from PGE2),DMSO: >100 mg/ml (from PGE2),Ethanol: >100 mg/ml (from PGE2),PBS pH 7.2: >5 mg/ml (from PGE2)
储存: Store at -20°C
库存: 现货

Background

9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimester of pregnancy. Meteneprost, when compared to PGE2 and PGF1α, in monkey and rat, does not result in unwanted side effects such as fever or gastrointestinal problems.