L-erythro Sphingosine (d18:1)

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500ug

￥1913.00

1530.00

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1mg

￥3600.00

2880.00

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L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1).

货号：ajci65782
CAS：6036-75-5
分子式：C18H37NO2
分子量：299.5
纯度：98%
存储：Store at -20°C
库存：现货

Background:

L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1) . It inhibits protein kinase C (PKC) in vitro (IC50 = 3.3 mol%) and superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils as well as reduces growth of CHO cells (IC50s = 1.3 and 2 μM, respectively). L-erythro Sphingosine also inhibits dephosphorylation of the tumor suppressor retinoblastoma gene product (pRb; EC50 = 5 μM) and growth of MOLT-4 acute lymphoblastic leukemia cells (IC50 = 3.7 μM).