Diflorasone Diacetate

A corticosteroid

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库存: 现货

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5mg

￥2187.00

1750.00

- +
10mg

￥3887.00

3110.00

- +

已选 0 种 0 瓶

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货号: ajci65976
CAS: 33564-31-7
别名: 醋酸双氟拉松；二醋酸二氟拉松
分子式: C26H32F2O7
分子量: 494.5
纯度: >98%
溶解度: Chloroform: Slightly Soluble,Methanol: Slightly Soluble
储存: Store at -20°C
库存: 现货

Background

Diflorasone is a corticosteroid with anti-inflammatory activity. It reduces production of the inflammatory cytokines Il-6, Il-4, and macrophage inflammatory protein-2 (Mip-2) and completely inhibits swelling in the ears of toluene-2,4-diisocyaniate-sensitized mice following topical administration of 20 µL of a 0.05% solution. Diflorasone inhibits RANTES and thymus and activation regulated chemokine (TARC) in a dinitrochlorobenzene-induced mouse model of allergic contact dermatitis. It also inhibits proliferation of human keratinocytes in vitro and reduces epidermal thickening in a mouse model of psoriasis induced by imiquimod .