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CAY10701

CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively).

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CAY10701的二维码
  • 库存: 现货
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  • 500ug
    ¥10162.00
    8130.00
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  • 1mg
    ¥19137.00
    15310.00
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  • 货号: ajci66022
  • CAS: 1616967-52-2
  • 别名:
  • 分子式: C24H19N3O2
  • 分子量: 381.4
  • 纯度: >98%
  • 溶解度: Ethanol: 10 mg/ml,Methanol: 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

CAY10701 is a 7-deazahypoxanthine analog that prevents microtubule formation, blocking the proliferation of HeLa and MCF-7 cells (GI50s = 22 and 38 nM, respectively). It also inhibits the growth of several different colorectal cancer cell lines (GI50 values range from 9 to 17 nM), while being at least 1,500-fold less effective against normal human fibroblast WI38 cells. CAY10701 is effective in vivo, reducing tumor volume in colorectal cell xenografts in mice without significantly altering body weight.

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