安捷凯生物医药
全部分类
全部分类
  • N-(n-Butyl)deoxygalactonojirimycin
N-(n-Butyl)deoxygalactonojirimycin的可视化放大

N-(n-Butyl)deoxygalactonojirimycin

An inhibitor of glucosylceramide synthase, glucocerebrosidase, and β-glucosidase 2

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

N-(n-Butyl)deoxygalactonojirimycin的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥737.00
    590.00
    - +
  • 1mg
    ￥1312.00
    1050.00
    - +
  • 5mg
    ￥3275.00
    2620.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
首页 收藏

使用我司产品发表的文章

  • 货号: ajci66712
  • CAS: 141206-42-0
  • 别名: N-(正丁基)脱氧半乳糖霉素,NB-DGJ; N-(n-Butyl)deoxygalactonojirimycin
  • 分子式: C10H21NO4
  • 分子量: 219.3
  • 纯度: >98%
  • 溶解度: DMF: 20 mg/mL,DMSO: 30 mg/mL,Ethanol: 5 mg/mL,PBS (pH 7.2): 10 mg/mL
  • 储存: Store at -20°C
  • 库存: 现货

Background

N-(n-Butyl)deoxygalactonojirimycin is an inhibitor of α-D-galactosidase. It has also been shown to prevent glucosylceramide biosynthesis both in vitro and in mouse models of lysosome storage disorders by inhibiting the ceramide-specific glucosyltransferase, UDP-glucose ceramide glucosyltransferase (IC50 = 41.4 µM) without affecting α-glucosidase I and II or β-glucocerebrosidase (IC50s > 1 mM). This compound has been used to sensitize cultured chronic lymphocytic leukemia cells to the chemotherapeutic agents cladribine , chlorambucil , and fludarabine .

没有评价数据

一键回到顶部
展开 收缩

安捷凯在线客服

扫一扫加微信

扫一扫加微信

温馨提示 ×
商品已成功加入购物车！
购物车共 0 件商品
去购物车结算