Misoprostol (free acid)

An EP2, EP3, and EP4 receptor agonist

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库存: 现货

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促销价

数量
1mg

￥800.00

640.00

- +
5mg

￥3600.00

2880.00

- +
10mg

￥6400.00

5120.00

- +
50mg

￥25787.00

20630.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajci67126
CAS: 112137-89-0
别名: 米索前列醇酸
分子式: C21H36O5
分子量: 368.5
纯度: >98%
溶解度: DMF: >100 mg/ml (from PGE1),DMSO: >50 mg/ml (from PGE1),Ethanol: >50 mg/ml (from PGE1),PBS pH 7.2: 1.67 mg/ml (from PGE1)
储存: Store at -20°C
库存: 现货

Background

Misoprostol is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 µg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.