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  • (±)-Clopidogrel (hydrochloride)
(±)-Clopidogrel (hydrochloride)的可视化放大

(±)-Clopidogrel (hydrochloride)

A prodrug of the platelet purinergic P2Y12 receptor antagonist

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(±)-Clopidogrel (hydrochloride)的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 10mg
    ￥2312.00
    1850.00
    - +
  • 50mg
    ￥10262.00
    8210.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci67578
  • CAS: 130209-90-4
  • 别名:
  • 分子式: C16H16ClNO2S?HCl
  • 分子量: 358.3
  • 纯度: >98%
  • 溶解度: DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Clopidogrel is an antithrombic compound whose active metabolite is a selective, irreversible antagonist of the platelet purinergic P2Y12 receptor (IC50 = 100 nM). Clopidogrel inhibits ADP-induced platelet aggregation ex vivo and functions as a prodrug whereupon biotransformation to its active metabolite via CYP2C19 in the liver enables its anti-aggregating activity. Marketed under the name Plavix?, clopidogrel in combination with aspirin has been shown to be beneficial in the prevention of vascular ischemic events for patients without deficiencies in CYP2C19-related metabolism.

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