安捷凯生物医药
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  • (±)-Nornicotine
(±)-Nornicotine的可视化放大

(±)-Nornicotine

An active metabolite of nicotine and nAChR agonist

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(±)-Nornicotine的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 50mg
    ￥375.00
    300.00
    - +
  • 100mg
    ￥562.00
    450.00
    - +
  • 250mg
    ￥1712.00
    1370.00
    - +
  • 500mg
    ￥3237.00
    2590.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci67594
  • CAS: 5746-86-1
  • 别名: 3-(吡咯烷-2-基)吡啶
  • 分子式: C9H12N2
  • 分子量: 148.2
  • 纯度: >98%
  • 溶解度: DMF: 50 mg/ml,DMSO: 30 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): 1 mg/ml
  • 储存: Store at 2-8°C
  • 库存: 现货

Background

(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. The α6 and α7 subunit-containing neuronal nAChRs are particularly responsive to nornicotine with EC50 values of approximately 4 and 17 µM, respectively, when expressed in Xenopus oocytes. Nornicotine promotes cell migration and destabilizes cell-cell junctions in an endothelial cell line. It is generally thought to be free from abuse potential, but it has been self-administered by rats. It can be detected in urine.

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