1,2-Dioleyloxy-3-dimethylamino-propane

An ionizable cationic lipid

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库存: 现货

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50mg

￥1112.00

890.00

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100mg

￥1987.00

1590.00

- +
250mg

￥4100.00

3280.00

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Background

1,2-Dioleyloxy-3-dimethylamino-propane is a cationic lipid containing the unsaturated long-chain (18:1) oleic acid inserted at both the sn-1 and sn-2 positions. It has been used in the composition of lipospomes formulated as stable nucleic acid lipid particles that can encapsulate siRNA or other small molecules to be used for drug delivery.[1] [2]

Reference:
[1]. Fenske, D.B., Chonn, A., and Cullis, P.R. Liposomal nanomedicines: An emerging field. Toxicologic Pathology 36(1), 21-29 (2008).
[2]. Heyes, J., Palmer, L., Bremner, K., et al. Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids. Journal of Controlled Release 107(2), 276-287 (2005).