17-phenyl trinor Prostaglandin F2α cyclopropyl methyl amide

A lipophilic analog of 17-phenyl trinor PGF2α

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1mg

￥1212.00

970.00

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5mg

￥5450.00

4360.00

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10mg

￥9687.00

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货号: ajci68182
CAS: 1138395-10-4
别名: 17phenyl trinor PGF2α cyclopropyl methyl amide
分子式: C27H39NO4
分子量: 441.6
纯度: >98%
溶解度: Acetonitrile: 3 mg/ml,DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): .25 mg/ml
储存: Store at -20°C
库存: 现货

Background

Prostaglandin F2α (PGF2α) activates the FP receptor, promoting smooth muscle contraction and luteolysis. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. It is produced in vivo by the hydrolysis of 17-phenyl trinor PGF2α ethyl amide. 17-phenyl trinor PGF2α ethyl amide is used to reduce intraocular pressure related to glaucoma. 17-phenyl trinor PGF2α cyclopropyl methyl amide is a lipophilic analog of 17-phenyl trinor PGF2α. Amides of PGs may serve as prodrugs, as they are hydrolyzed in certain tissues to generate the bioactive free acid.