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  • 20-carboxy Leukotriene B4
20-carboxy Leukotriene B4的可视化放大

20-carboxy Leukotriene B4

A LTB4 metabolite

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20-carboxy Leukotriene B4的二维码
  • 库存: 现货
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  • 25ug
    ￥2912.00
    2330.00
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  • 50ug
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    4400.00
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  • 100ug
    ￥10437.00
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  • 货号: ajci68406
  • CAS: 80434-82-8
  • 别名: 20-羧基白三烯B4
  • 分子式: C20H30O6
  • 分子量: 366.5
  • 纯度: >98%
  • 溶解度: DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
  • 储存: Store at -20°C
  • 库存: 现货

Background

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

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