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  • 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)的可视化放大

2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

A natural precursor of dGTP

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2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)的二维码
  • 库存: 现货
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  • 500mg
    ¥712.00
    570.00
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    ¥1100.00
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    ¥4300.00
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  • 货号: ajci68544
  • CAS: 146877-98-7
  • 别名: dGMP
  • 分子式: C10H12N5O7P?2Na [XH2O]
  • 分子量: 391.2
  • 纯度: >98%
  • 溶解度: PBS (pH 7.2): 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. In addition, dGMP can be efficiently phosphorylated by the type I thymidylate kinase of the malarial agent P. falciparum. In humans, deficiency of mitochondrial deoxyguanosine kinase, which synthesizes dGMP from ATP and deoxyguanosine, contributes to mitochondrial DNA depletion syndrome.

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