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  • Adefovir
Adefovir的可视化放大

Adefovir

An active metabolite of adefovir dipivoxil

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Adefovir的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 10mg
    ¥287.00
    230.00
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  • 25mg
    ¥550.00
    440.00
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  • 50mg
    ¥875.00
    700.00
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  • 100mg
    ¥1300.00
    1040.00
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  • 货号: ajci69704
  • CAS: 106941-25-7
  • 别名: 阿德福韦; GS-0393; PMEA
  • 分子式: C8H12N5O4P
  • 分子量: 273.2
  • 纯度: >98%
  • 溶解度: 0.1 M NaOH : 10 mg/mL (36.60 mM; ultrasonic and adjust pH to 10 with NaOH)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor. When evaluated in animal and clinical models of infections, its antiviral spectrum was shown to uniquely encompass activity against herpes viruses (HSV-1, HSV-2, VZV, CMV, EBV, HHV-6, HHV-7, and HHV-8), hepatitis B virus (HBV), and HIV (HIV-1, HIV-2, SIV, and FIV). Adefovir-associated resistance mutations have not yet been observed in HBV resistance surveillance clinical studies.

Protocol

Animal experiment

Animal Models: Ducks
Formulation: dissolved in phosphate-buffered saline and adjusted to pH to 7.3
Dosages: 15 and 30 mg/kg/day
Administration: i.p.

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