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  • Aminopterin
Aminopterin的可视化放大

Aminopterin

A synthetic folic acid derivative

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Aminopterin的二维码
  • 库存: 现货
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  • 包装
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    促销价
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  • 5mg
    ¥387.00
    310.00
    - +
  • 10mg
    ¥700.00
    560.00
    - +
  • 25mg
    ¥1262.00
    1010.00
    - +
  • 50mg
    ¥2362.00
    1890.00
    - +
已选 0 0
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  • 货号: ajci69820
  • CAS: 54-62-6
  • 别名: 氨基蝶呤; 4-Aminofolic acid; APGA
  • 分子式: C19H20N8O5
  • 分子量: 440.4
  • 纯度: >98%
  • 溶解度: DMF: ,DMSO: ,Ethanol: Slightly,Water: Partly
  • 储存: Store at -20°C
  • 库存: 现货

Background

Aminopterin is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase, which is a cofactor for nucleic acid synthesis. Aminopterin has anticancer and immunosuppressive properties. Formulations containing it have been used for pediatric leukemia though methotrexate is now more commonly used due to a more favorable therapeutic index. Aminopterin is a component of the widely used HAT (hypoxanthine-aminopterin-thymidine) medium to select cells for mammalian cell culture.

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