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Brassinin

An anticancer phytoalexin

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Brassinin的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 1mg
    ¥512.00
    410.00
    - +
  • 5mg
    ¥1175.00
    940.00
    - +
  • 10mg
    ¥2062.00
    1650.00
    - +
  • 25mg
    ¥4500.00
    3600.00
    - +
已选 0 0
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  • 货号: ajci70190
  • CAS: 105748-59-2
  • 别名: 芸苔宁,Brassinine
  • 分子式: C11H12N2S2
  • 分子量: 236.4
  • 纯度: >98%
  • 溶解度: DMF: 10 MG/ML,DMSO: 10 MG/ML,Ethanol: 10 MG/ML
  • 储存: Store at -20°C
  • 库存: 现货

Background

Brassinin (BSN) is a phytoalexin isolated from B. campestris that exhibits anticancer, chemopreventative, antiproliferative, and antifungal activities. Brassinin suppresses constitutive and IL-6-induced STAT3 activation in vitro and attenuates tumor growth in a xenograft lung cancer mouse model through modulation of E3 SUMO-protein ligase 3 (PIAS-3) and suppressor of cytokine signaling-3 (SOCS-3). Brassinin also induces apoptosis in PC3 cells through suppression of PI3K, Akt, mTOR, and S6K1.

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