CAY10568

A blocker of voltage-gated Na+?channels

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
10mg

￥600.00

480.00

- +
25mg

￥1425.00

1140.00

- +
50mg

￥2712.00

2170.00

- +
100mg

￥4762.00

3810.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci70584
CAS: 22913-17-3
别名: Santinamide
分子式: C11H17N2O?I
分子量: 320.2
纯度: >98%
溶解度: DMF: 5 mg/ml,DMSO: 3 mg/ml,PBS (pH 7.2): 0.5 mg/ml
储存: Store at -20°C
库存: 现货

Background

Most local anesthetics act by abolishing voltage gated sodium channel currents indiscriminately in all populations of neurons. Selective analgesia through TRPV1-mediated entry of a cationic lidocaine derivative, QX314, was recently reported. CAY10568 is a physically smaller, less hydrophobic version of QX314 designed to be even more permeable to TRPV1 ion channel when activated by agonists such as capsaicin and N-oleoyl dopamine. CAY10568 when given in combination with suitable TRPV1 agonists should produce selective blockade of the pain response while leaving motor, touch, and proprioception intact.