安捷凯生物医药
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  • CAY10578
CAY10578的可视化放大

CAY10578

A potent and selective CK2 inhibitor

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

CAY10578的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 1mg
    ￥262.00
    210.00
    - +
  • 5mg
    ￥1212.00
    970.00
    - +
  • 10mg
    ￥2150.00
    1720.00
    - +
  • 25mg
    ￥4675.00
    3740.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci70596
  • CAS: 19231-60-8
  • 别名:
  • 分子式: C10H3I4NO4
  • 分子量: 708.8
  • 纯度: >98%
  • 溶解度: DMF: 10 mg/ml,DMF:PBS (pH 7.2) 1:5: 0.15 mg/ml,DMSO: 5 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, Cdk5, and MSK1).

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