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  • Cholic Acid 7-sulfate
Cholic Acid 7-sulfate的可视化放大

Cholic Acid 7-sulfate

A metabolite of cholic acid

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Cholic Acid 7-sulfate的二维码
  • 库存: 现货
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  • 500ug
    ¥937.00
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  • 1mg
    ¥1775.00
    1420.00
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  • 5mg
    ¥7387.00
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    ¥12812.00
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  • 货号: ajci70770
  • CAS: 60320-05-0
  • 别名: 胆酸7-硫酸盐,7-Sulfocholic acid
  • 分子式: C24H40O8S
  • 分子量: 488.6
  • 纯度: >98%
  • 溶解度: 0.3mg/mL in DMSO, 1mg/mL in DMF
  • 储存: Store at -20°C
  • 库存: 现货

Background

Cholic acid 7-sulfate is a metabolite of the primary bile acid cholic acid.[1],[2] It is produced by conjugation of a sulfate group with the hydroxy group at position 7 of cholic acid in the liver and gut. Fecal levels of cholic acid 7-sulfate are increased in male, but not female, mice fed a diet supplemented with cholic acid or chenodeoxycholic acid.[2]


Reference:
[1]. Alnouti, Y. Bile acid sulfation: A pathway of bile acid elimination and detoxification. Toxicological Sciences 108(2), 225-246 (2009).
[2]. Zhang, Y., and Klaassen, C.D. Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice. J. Lipid Res. 51(11), 3230-3242 (2010).

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