A glucosinolate
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Glucotropaeolin is a glucosinolate that has been found in cruciferous plants such as L. sativum. It has antiprotozoal activity against HM1-IMSS E. histolytica, reducing the number of trophozoites with an IC50 value of 20.4 µg/ml. Dietary administration of glucotropaeolin (1,000 mg/kg), unlike administration of whole glucosinolate extract, does not induce the activity of anticarcinogenic mixed-function oxidases in rat large intestines. Glucotropaeolin is inactive against the fungi F. culmorum and does not have antitumor activity, however, it is metabolized into isothiocyanate products that have these activities.
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