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  • GSK121 (trifluoroacetate salt)
GSK121 (trifluoroacetate salt)的可视化放大

GSK121 (trifluoroacetate salt)

A PAD4 inhibitor

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

GSK121 (trifluoroacetate salt)的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥187.00
    150.00
    - +
  • 1mg
    ￥337.00
    270.00
    - +
  • 5mg
    ￥1662.00
    1330.00
    - +
  • 10mg
    ￥2912.00
    2330.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci71818
  • CAS: 1652591-80-4
  • 别名:
  • 分子式: C23H25N5O?CF3COOH
  • 分子量: 501.5
  • 纯度: >98%
  • 溶解度: DMF: 30 mg/ml,DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml,PBS (pH 7.2): 10 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK121 is the initial compound identified in a screen for PAD4 inhibitors and was optimized to produce the more potent PAD4 inhibitors, GSK484 and GSK199 . GSK121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC50 value of 3.2 µM.

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