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  • Helenalin
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Helenalin

An anti-inflammatory sesquiterpene lactone

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Helenalin的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 500ug
    ￥4262.00
    3410.00
    - +
  • 1mg
    ￥6400.00
    5120.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajci71862
  • CAS: 6754-13-8
  • 别名: 心菊内酯
  • 分子式: C15H18O4
  • 分子量: 262.3
  • 纯度: >98%
  • 溶解度: DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 0.2 mg/ml
  • 储存: Store at -20°C
  • 库存: 现货

Background

Helenalin is a sesquiterpene lactone first isolated from various species of Arnica. It has anti-inflammatory effects, most notably by inhibiting gene expression mediated by NF-κB at doses from 1 to 20 µM. Like other sesquiterpene lactones, helenalin can modify sulfhydryl groups of cysteine residues and it alkylates these groups on the p65 subunit of NF-κB. It also suppresses the proliferation of cancer cells through multiple mechanisms, including the prevention of signaling through NF-κB. Helenalin has antibacterial and anti-protozoal activities.

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