L-Selenocystine

A diselenide-bridged amino acid

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库存: 现货

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包装

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促销价

数量
50mg

￥425.00

340.00

- +
100mg

￥825.00

660.00

- +
250mg

￥1950.00

1560.00

- +
1g

￥3025.00

2420.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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Background

L-Selenocystine is a diselenide-bridged amino acid that may be confused with selenocysteine (Sec), which is a rare amino acid featuring a single selenium atom. L-Selenocystine is a redox-active selenium compound that has both anti- and pro-oxidant actions. This compound can be reduced by low molecular thiols and disulfide reductases to Sec. It is reduced to Sec by mammalian thioredoxin reductase (apparent Km = 6.0 µM), and this property can be used to assay thioredoxin reductase activity. L-Selenocystine induces an unfolded protein response, ER stress, and large cytoplasmic vacuolization in HeLa cells and has cytostatic effects in a range of cancer cell types.