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  • NVS-CECR2-1
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NVS-CECR2-1

A potent and selective CECR2 inhibitor

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NVS-CECR2-1的二维码
  • 库存: 现货
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  • 包装
    价格
    促销价
    数量
  • 1mg
    ¥1362.00
    1090.00
    - +
  • 5mg
    ¥3687.00
    2950.00
    - +
  • 10mg
    ¥6700.00
    5360.00
    - +
  • 25mg
    ¥13250.00
    10600.00
    - +
已选 0 0
金额: ¥0.00
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  • 货号: ajci73196
  • CAS: 1992047-61-6
  • 别名: NVS-1
  • 分子式: C27H37N5O2S
  • 分子量: 495.7
  • 纯度: >98%
  • 溶解度: DMSO: 0.3 mg/mL
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

NVS-CECR2-1 is a potent inhibitor of CECR2 (cat eye syndrome chromosome region, candidate 2), a component of chromatin complexes that regulate gene expression controlling development. It binds CECR2 with high affinity (IC50 = 0.047 µM by Alpha screen, Kd = 0.80 µM by ITC). NVS-CECR2-1 demonstrates no crossreactivity in a panel of 48 bromodomains and has no major activity in kinase, protease, and receptor panels. It shows robust activity in cells by FRAP assay, due to its slow off-rate, and has no acute toxicity. See the Structural Genomics Consortium (SGC) website for more information.

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