Prostaglandin F2α-1-glyceryl ester

A stable metabolite of PGF2α

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库存: 现货

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500ug

￥712.00

570.00

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1mg

￥1225.00

980.00

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5mg

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货号: ajci73692
CAS: 43042-79-1
别名: PGF2α1glyceryl ester
分子式: C23H40O7
分子量: 428.6
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 20 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 500 μ g/ml
储存: Store at -20°C
库存: 现货

Background

2-Arachidonoyl glycerol has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor. Incubation of 2-AG with cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation. The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.