An impurity found in risperidone
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Risperidone E-oxime is a potential impurity found in commercial preparations of risperidone. Risperidone is a longer-acting benzisoxazole derivative used for treating schizophrenia, and also the psychotic, affective, or behavioral symptoms associated with other disorders. This second-generation antipsychotic was designed to antagonize both D2 and 5-HT2A receptors. It has little effect on cholinergic and β-adrenergic receptors but does affect α2-adrenergic and histamine H1 receptors.
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