S-(5'-Adenosyl)-L-methionine chloride (hydrochloride)

Ubiquitous methyl donor

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库存: 现货

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1mg

￥675.00

540.00

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2.5mg

￥1512.00

1210.00

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5mg

￥2687.00

2150.00

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货号: ajci73960
CAS: 86867-01-8
别名: 5'-[[(3S)-3-氨基-3-羧基丙基]甲基锍]-5'-脱氧腺苷氯化物二盐酸盐
分子式: C15H23ClN6O5S?2HCl
分子量: 507.8
纯度: >98%
溶解度: Methanol: 1 mg/ml,Water: 5 mg/ml
储存: Store at -80°C
库存: 现货

Background

S-(5'-Adenosyl)-L-methionine chloride (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases. The transfer of a methyl group from SAM to an acceptor produces S-adenosyl-L-homocysteine . SAM is also metabolized by SAM decarboxlase to give decarboxylated SAM, which is involved in the polyamine pathway that generates spermine. Chemical's SAM has been purified to remove all S-adenosylhomocysteine, a known inhibitor of most SAM-dependent methyltransferases which is commonly found in other commercially available SAM. In addition, 's SAM contains no S-methylthioadenosine, a common impurity which may act as a substrate in some assay formats, resulting in high background.