TEMPONE

A 4-oxo derivative of the spin trap TEMPO

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1g

￥450.00

360.00

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5g

￥1475.00

1180.00

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10g

￥2512.00

2010.00

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25g

￥5087.00

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货号: ajci74262
CAS: 2896-70-0
别名: 4-氧-2,2,6,6-四甲基哌啶-1-氧自由基
分子式: C9H16NO2
分子量: 170.2
纯度: >98%
溶解度: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存: Store at -20°C
库存: 现货

Background

2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this nitroxyl radical can be used in hydrogen transfer experiments and as a polarizing agent in dynamic nuclear polarization NMR spectroscopy. TEMPONE and other nitroxyl radicals have also been shown to reduce mean arterial pressure in spontaneously hypertensive rats when administered intravenously.