β-Apooxytetracycline

A potential impurity found in commercial preparations of oxytetracycline

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库存: 现货

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数量
500ug

￥650.00

520.00

- +
1mg

￥1250.00

1000.00

- +
5mg

￥5250.00

4200.00

- +
10mg

￥9862.00

7890.00

- +

已选 0 种 0 瓶

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货号: ajci74692
CAS: 18751-99-0
别名: 载脂蛋白-土霉素
分子式: C22H22N2O8
分子量: 442.4
纯度: >98%
溶解度: DMF: 12 mg/ml,DMSO: 20 mg/ml,Ethanol: 5 mg/ml,PBS (pH 7.2): 0.2 mg/ml
储存: Store at -20°C
库存: 现货

Background

β-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. β-Apooxytetracycline is a degradation product formed from oxytetracycline via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli. β-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.