Sulcotrione

Sulcotrione是β-三酮除草剂，可以抑制羟基苯基丙酮酸双加氧酶(HPPD)。

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50mg

￥700.00

560.00

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100mg

￥1075.00

860.00

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Background

Sulcotrione is a β-triketone herbicide which can inhibit hydroxyphenylpyruvate dioxygenase (HPPD).

The results show that sulcotrione behaves as time-independent reversible inhibitor. Similar results are previously described for natural β-triketones, and for the synthetic β-triketone NTBC. However it is the first time that such behavior is observed using a purified hydroxyphenylpyruvate dioxygenase (HPPD) and a synthetic β-triketone, namely sulcotrione. Inhibition kinetic analysis, performing with 3 hydroxyphenylpyruvate (HPP) and sulcotrione concentrations, show that the apparent KM increasing with sulcotrione concentration. This behavior is consistent with the data present in the literature, describing sulcotrione as a competitive inhibitor of HPPD[1].

[1]. Rocaboy-Faquet E, et al. A novel amperometric biosensor for ?-triketone herbicides based on hydroxyphenylpyruvatedioxygenase inhibition: A case study for sulcotrione. Talanta. 2016;146:510-6.

Protocol

Kinase experiment:

Electrochemical behavior of sulcotrione at 0.2 mg/L is characterized by cyclic voltammetry. Preliminary HPPD inhibition assays are performed by incubating the enzyme during time periods ranging from 2 to 10 min in presence of sulcotrione at differnt concentrations[1].

参考文献:

[1]. Rocaboy-Faquet E, et al. A novel amperometric biosensor for -triketone herbicides based on hydroxyphenylpyruvatedioxygenase inhibition: A case study for sulcotrione. Talanta. 2016;146:510-6.