Skatole(3-Methylindole)

Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

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100mg

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货号: ajce45534
CAS: 83-34-1
别名: 粪臭素; 3-Methylindole; 3-Methyl-1H-indole
分子式: C9H9N
分子量: 131.17
纯度: >98%
溶解度: DMSO: 100 mg/mL (762.37 mM)
储存: Store at -20°C
库存: 现货

Background

Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

3MI causes pulmonary edema in goats, sheep, rats, and some strains of mice. Response to 3-methylindole (3MI) varies among species. Mice recover from 3MI-induced bronchiolar epithelial injury but sustain persistent olfactory mucosal injury with scarring and epithelial metaplasia. In contrast, 3MI induces obliterative bronchiolitis in horses and ponies. It also causes severe olfactory mucosal damage and fibrosis in rodents (in addition to small airways disease)[2].

[1] Doran E, et al. Chem Biol Interact. 2002, 140(1):81-92. [2] Miller MA, et al. Vet Pathol. 2003, 40(4):363-70.