Gln-AMS是一种氨基酰基-tRNA合成酶(AARS)抑制剂,与非核糖体多肽合成酶(NRPS)A结构域结合。
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Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes.
[1]. Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402. [2]. Atta-ur-Rahman, et al. Frontiers in Natural Product Chemistry.
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