DL-Homocysteine thiolactone hydrochloride

A derivative of DL-homocysteine

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1g

￥537.00

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货号: ajce45756
CAS: 6038-19-3
别名: DL-高半胱氨酸硫内酯盐酸盐
分子式: C4H8ClNOS
分子量: 153.63
纯度: >98%
溶解度: DMF: 15 mg/ml,DMSO: 30 mg/ml,PBS (pH 7.2): 10 mg/ml
储存: Store at -20°C
库存: 现货

Background

DL-Homocysteine thiolactone is a derivative of DL-homocysteine .¹ It inhibits the growth of B. campestris, L. sativa, and E. utilis roots when used at a concentration of 50 ?M.² DL-Homocysteine thiolactone (10 ?M) decreases the maximum rate of left ventricular developed pressure, systolic left ventricular pressure, and coronary flow in isolated rat hearts.³ It induces arteriosclerotic plaque formation in rabbits when administered at a dose of 30 mg/kg for eight weeks.¹ DL-Homocysteine thiolactone has also been used as a precursor in the synthesis of thiolactone-containing monomers for use in polymer-based formaldehyde-scavenging coatings.⁴

1.McCully, K.S., and Wilson, R.B.Homocysteine theory of arteriosclerosisAtherosclerosis22(2)215-227(1975) 2.Inamori, Y., Muro, C., Toyoda, M., et al.Root-growth inhibition by ??-homocysteine thiolactone and its related compoundsBiosci. Biotech. Biochem.59(3)523-525(1995) 3.Zivkovic, V., Jakovljevic, V., Pechanova, O., et al.Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: The role of different gasotransmittersBiomed. Res. Int.318471(2013) 4.Resetco, C., Frank, D., Diki?, T., et al.Thiolactone-based polymers for formaldehyde scavenging coatingsEur. Polym. J.82166-174(2016)