安捷凯生物医药
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  • CX-157
CX-157的可视化放大

CX-157

CX-157是一个可逆的单胺氧化酶-A(MAO-A)抑制剂，其EC50值为19.3ng/mL。

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CX-157的二维码
  • 库存: 现货
可选规格
  • 包装
    价格
    促销价
    数量
  • 1mg
    ￥10050.00
    8040.00
    - +
  • 5mg
    ￥15912.00
    12730.00
    - +
  • 10mg
    ￥25462.00
    20370.00
    - +
已选 0 种 0 瓶
金额: ￥0.00
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使用我司产品发表的文章

  • 货号: ajce46552
  • CAS: 205187-53-7
  • 别名:
  • 分子式: C14H8F4O4S
  • 分子量: 348.27
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: Store at -20°C
  • 库存: 现货

Background

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.


CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters[1].


[1]. Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35(3):623-31.

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