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  • Kuwanon A
Kuwanon A的可视化放大

Kuwanon A

KuwanonA是从桑树(MorusalbaL.)的根皮中分离的的黄酮衍生物,抑制一氧化氮产生的IC50值为10.5μM。

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Kuwanon A的二维码
  • 库存: 现货
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  • 2mg
    ¥1575.00
    1260.00
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  • 5mg
    ¥3162.00
    2530.00
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  • 货号: ajce47024
  • CAS: 62949-77-3
  • 别名: 桑皮酮A
  • 分子式: C25H24O6
  • 分子量: 420.45
  • 纯度: >98%
  • 溶解度: Soluble in DMSO
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

Kuwanon A is a flavone derivative isolated from the root barks of the mulberry tree (Morus alba L.); inhibits nitric oxide production with an IC50 of 10.5 μM.


Kuwanon A shows significant inhibitory activity towards the differentiation of 3T3-L1 adipocytes with TG inhibition values of 47.1%. Kuwanon A also shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells with an IC50 of 10.5 μM[1].


[1]. Yang ZG, et al. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011 Jul 19;16(7):6010-22.

Protocol

Cell experiment:

RAW264.7 cells are treated with Kuwanon A (3, 10, 20, 30, 100 μM). Cell viability is measured using the MTT assay[1].

参考文献:

[1]. Yang ZG, et al. Inhibitory effects of constituents from Morus alba var. multicaulis on differentiation of 3T3-L1 cells and nitric oxide production in RAW264.7 cells. Molecules. 2011 Jul 19;16(7):6010-22.

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