Deriglidole (SL 86-0715) 是一种外周肾上腺素受体拮抗剂,对 α2-肾上腺素受体具有高亲和力。
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Deriglidole is a peripheral adrenoceptor antagonist with a high affinity for α2-adrenoceptors.
Deriglidole is a selective α2-receptor inhibitor. Deriglidole inhibits [3H]Clonidine and [3H]Idazoxan but not [3H]Prazosin binding to rat cortical and human platelet α2-adrenoceptors and is more selective than Idazoxan for peripheral receptors[1].
[1]. Natali A, et al. Effects of acute alpha 2-blockade on insulin action and secretion in humans. Am J Physiol. 1998 Jan;274(1 Pt 1):E57-64.
Noradrenaline bitartrate monohydrate
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