Histatin 5

An antimicrobial peptide

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库存: 现货

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500ug

￥1300.00

1040.00

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1mg

￥1962.00

1570.00

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5mg

￥6800.00

5440.00

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10mg

￥10687.00

8550.00

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Background

Histatin 5 is a salivary antimicrobial peptide.^1,2,3 It is active against C. albicans (LC₅₀ = 1.8 ?M), as well as A. baumannii, P. aeruginosa, and E. cloacae (MICs = 38, 47, and 90 ?M, respectively).^1,2 Topical application of histatin 5 (20 ?M) decreases fungal burden in a mouse model of C. albicans-induced vulvovaginal candidiasis.³

1.Edgerton, M., Koshlukova, S.E., Lo, T.E., et al.Candidacidal activity of salivary histatinsJ. Biol. Chem.273(32)20438-20447(1998) 2.Du, H., Puri, S., McCall, A., et al.Human salivary protein histatin 5 has potent bactericidal activity against ESKAPE pathogensFront. Cell. Infect. Microbiol.741(2017) 3.Liao, H., Liu, S., Wang, H., et al.Efficacy of Histatin5 in a murine model of vulvovaginal candidiasis caused by Candida albicansPathog. Dis.75(6)(2017)