Deprodone propionate (RD20000) (RD20000) 是一种皮质类固醇,通过用丙酸酯化泼尼松龙骨架的 17 位并将其 21 位脱氧而获得。
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Deprodone propionate (RD20000) is a corticosteroid which is obtained by esterifying with propionic acid the 17-position of the prednisolone skeleton and deoxidating its 21-position.
Deprodone propionate as an effective ingredient, can exhibit its effects to the maximum extent and over a prolonged period of time, do not have skin irritation, and are physicochemically stable. Deprodone propionate can be maintained in a stably suspended state owing to the thickening action of the suspending agent[1].
[1]. Takashi Narui, et al. Water and deprodone proprionate -containing external preparations. EP 0473810 B1.
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