Dinotefuran (MTI-446)

A neonicotinoid insecticide

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
50mg

￥537.00

430.00

- +
100mg

￥862.00

690.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

Background

Dinotefuran is a neonicotinoid insecticide.¹ It is an agonist of nicotinic acetylcholine receptors (nAChRs), inducing inward currents in isolated American cockroach (P. americana) neurons with an EC₅₀ value of 7.6 ?M. Dinotefuran, alone or in combination with the metabolic inhibitors piperonyl butoxide or propargyl propyl benzenephosphonate (NIA), induces mortality in adult P. americana.² It is lethal to insecticide-sensitive or -resistant strains of A. gambiae, C. quinquefasciatus, and A. aegypti in larval (LC₅₀s = 0.14-0.44 mg/L) and adult (LD₅₀s = 0.18-31.16 ng/mg) bioassays.³ Dinotefuran has been found in a variety of commercial foodstuffs, including rice, cucumber, milk, egg, and pork samples, as well as in water samples from freshwater streams.^4,5 Formulations containing dinotefuran have been used in the agricultural and veterinary control of insect infestations.

1.Tan, J., Galligan, J.J., and Hollingworth, R.M.Agonist actions of neonicotinoids on nicotinic acetylcholine receptors expressed by cockroach neuronsNeurotoxicology28(4)829-842(2007) 2.Kiriyama, K., and Nishimura, K.Structural effects of dinotefuran and analogues in insecticidal and neural activitiesPest Manag. Sci.58(7)669-676(2002) 3.Corbel, V., Duchon, S., Zaim, M., et al.Dinotefuran: A potential neonicotinoid insecticide against resistant mosquitoesJ. Med. Entomol.41(4)712-717(2004) 4.Zhang, Y., Wu, X., Duan, T., et al.Ultra high performance liquid chromatography with tandem mass spectrometry method for determining dinotefuran and its main metabolites in samples of plants, animal-derived foods, soil, and waterJ. Sep. Sci.41(14)2913-2923(2018) 5.Hladik, M.L., and Kolpin, D.W.First national-scale reconnaissance of neonicotinoid insecticides in streams across the USAEnviron. Chem.1312-20(2016)