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  • Docosatrienoic Acid (cis-13,16,19-docosatrienoic acid)
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Docosatrienoic Acid (cis-13,16,19-docosatrienoic acid)

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Docosatrienoicacid是罕见的ω-3脂肪酸;抑制LTB4与中性粒细胞膜的结合的Ki值为5μM。

货号:ajce49398
CAS:28845-86-5
分子式:C22H38O2
分子量:334.54
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Docosatrienoic acid is a rare ω-3 fatty acid; inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM.


Docosatrienoic acid inhibits LTB4 binding to pig neutrophil membranes with an Ki of 5 μM[1].


Application of docosatrienic acid dose-dependently decreases the peak K+ current amplitide and accelerates the potassium activation and inactivation kinetics at all rat membrane potentials[2].


[1]. Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7. [2]. Krutetskaia ZI, et al. The effect of docosatrienoic acid on the potassium channels of outward rectification in the membrane of rat peritoneal macrophages. Fiziol Zh Im I M Sechenova. 1995 Jul;81(7):111-9.


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